Caution About Folic Acid Supplements
Beware of the interaction between vitamin B12 and folic acid
Intake of supplemental folic acid should not exceed 1,000 micrograms (¥ìg) per day to prevent folic acid from triggering symptoms of vitamin B12 deficiency. Folic acid supplements can correct the anemia associated with vitamin B12 deficiency. Unfortunately, folic acid will not correct changes in the nervous system that result from vitamin B12 deficiency. Permanent nerve damage can occur if vitamin B12 deficiency is not treated.

It is very important for older adults to be aware of the relationship between folic acid and vitamin B12 because they are at greater risk of having a vitamin B12 deficiency. If you are 50 years of age or older, ask your physician to check your B12 status before you take a supplement that contains folic acid. If you are taking a supplement containing folic acid, read the label to make sure it also contains B12 or speak with a physician about the need for a B12 supplement.

What is the health risk of too much folic acid?

Folate intake from food is not associated with any health risk. The risk of toxicity from folic acid intake from supplements and/or fortified foods is also low. It is a water soluble vitamin, so any excess intake is usually excreted in urine. There is some evidence that high levels of folic acid can provoke seizures in patients taking anti-convulsant medications. Anyone taking such medications should consult with a medical doctor before taking a folic acid supplement.

The Institute of Medicine has established a tolerable upper intake level (UL) for folate from fortified foods or supplements (i.e. folic acid) for ages one and above. Intakes above this level increase the risk of adverse health effects. In adults, supplemental folic acid should not exceed the UL to prevent folic acid from triggering symptoms of vitamin B12 deficiency. It is important to recognize that the UL refers to the amount of synthetic folate (i.e. folic acid) being consumed per day from fortified foods and/or supplements. There is no health risk, and no UL, for natural sources of folate found in food. Table 4 lists the Upper Intake Levels (UL) for folate, in micrograms (mcg), for children and adults.

Table 4: Tolerable Upper Intake Levels for Folate for Children and Adults
Age
(years)
Males and Females
(mcg/day)
Pregnancy
(mcg/day)
Lactation
(mcg/day)
1-3 300 N/A N/A
4-8 400 N/A N/A
9-13 600 N/A N/A
14-18 800 800 800
19 + 1000 1000 1000

Selecting a healthful diet

As the 2000 Dietary Guidelines for Americans states, "Different foods contain different nutrients and other healthful substances. No single food can supply all the nutrients in the amounts you need". As indicated in Table 1, green leafy vegetables, dried beans and peas, and many other types of vegetables and fruits provide folate. In addition, fortified foods are a major source of folic acid. It is not unusual to find foods such as some ready-to-eat cereals fortified with 100% of the RDA for folate. The variety of fortified foods available has made it easier for women of childbearing age in the US to consume the recommended 400 mcg of folic acid per day from fortified foods and/or supplements. The large numbers of fortified foods on the market, however, also raises the risk of exceeding the UL. This is especially important for anyone at risk of vitamin B12 deficiency, which can be triggered by too much folic acid. It is important for anyone who is considering taking a folic acid supplement to first consider whether their diet already includes adequate sources of dietary folate and fortified food sources of folic acid.

For more information about building a healthful diet, refer to the Dietary Guidelines for Americans
http://www.usda.gov/cnpp/DietGd.pdf and the US Department of Agriculture's Food Guide Pyramid http://www.nal.usda.gov/fnic/Fpyr/pyramid.html.

Office of Dietary Supplements
National Institutes of Health
Bethesda, Maryland 20892 USA
Web:
http://ods.od.nih.gov


 

 

Category: Supplements  |  Hit: 8594  |  Rating: 7  | 


Rate!
 
There is no comment



Add a comment !

Name:


E-Mail:


Comment:


                               

Bold | Italic | Underline | Link



Code:




Usa-Health-Center

+ Appearance

+ Bodybuilding

+ Conservation

+ Exercise

+ Food

+ Health and Wellness

+ Health Conditions

+ Nutrition

+ Others

+ Sexual Wellness

+ Supplements

Search


Top 12

10 Benefits of Having Attention Deficit Disorder (ADD)

Diabetic Food, What kinds of foods can I eat?

Caution About Folic Acid Supplements

Love could be cured

How do I know if I have heart or cardiovascular disease? Are there any tests?

Dogs give women breast cancer

How Does Acne Develop?

Short-sighted people are more intelligent

Omega-3 Fatty Acids, Skin Disorders

Cinnamon Bark

Serving Sizes

What Is Horny Goat Weed?

Live tv
Msn Smileys

Privacy Policy